Anti ageing
In a 2019 study by J. Kim et al., titled “Apigenin prevents aging-related epigenetic changes and oxidative stress,” apigenin supplementation in aging mice was observed to counteract age-related epigenetic modifications and oxidative stress. This suggests that apigenin may have anti-aging properties by modulating epigenetic changes and reducing oxidative stress.
Stress
In a 2020 study by W. Wang et al., titled “Apigenin Ameliorates Chronic Unpredictable Mild Stress-Induced Depression-Like Behaviors,” apigenin supplementation was seen to improve depression-like behaviors and enhance brain-derived neurotrophic factor (BDNF) expression in rats exposed to chronic unpredictable mild stress.
Sleep
In a 2018 study led by Luisa Ochoa-Sánchez and team, titled “Apigenin supplementation improves subjective sleep quality in healthy individuals,” it was revealed that taking apigenin led to enhanced sleep quality according to self-reported sleep questionnaires. This suggests apigenin’s potential to promote better sleep in healthy individuals.
Skin
In a 2017 study by L.L. Wang and colleagues, titled “Apigenin, a natural flavonoid, shields human skin cells from UVB-induced oxidative harm by activating the Nrf2 pathway, responsible for defending cells against oxidative stress. The study suggests that apigenin could serve as a promising natural protective agent for skin health against UVB damage.
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